PATHOGENETIC ASPECTS OF THE USE OF LASER RADIATION IN THE TREATMENT OF CHRONIC HEPATITIS

Author(s):  N.M Burduli, Dr., Prof., North Ossetian State Medical Academy, Vladikavkaz, Russia, anastasya.krifaridi@yandex.ru

A.S. Krifaridi, candidate of Sciences, North Ossetian State Medical Academy, Vladikavkaz, Russia, anastasya.krifaridi@yandex.ru

I.Z. Aksenova, candidate of Sciences, associate Professor, North Ossetian State Medical Academy, Vladikavkaz, Russia

Issue:  Volume 42, № 1

Rubric:  Internal diseases

Annotation:  The aim of the work was to study the effect of low-intensity laser radiation on the cytokine system, vascular endothelial function in patients with chronic hepatitis. All patients were divided into three groups: in the I – th (control) group (30 people) only traditional drug therapy was used for treatment, patients of the II – th group (45 people) along with drug therapy received intravenous laser therapy and the III group of patients (45 people) received a course of cutaneous laser therapy. The results of our study indicate that drug therapy in patients with CG is not accompanied by a significant improvement in the plasma levels of NOx, as well as Pro-inflammatory cytokines, and the inclusion of laser therapy in the complex of therapeutic measures contributes to a significant improvement in the plasma levels of NOx, eliminating the imbalance of cytokine regulation. Various methods of laser therapy improve the NO-producing function of the endothelium, improve the functional state of the vascular endothelium, have an immunomodulatory effect.

Keywords:  endothelial dysfunction, nitric oxide, cytokines, chronic hepatitis, low-intensity laser therapy.

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