New in the studies of biodegradation of white phosphorus

Author(s):  A.Z. Mindubaev, candidate of Sciences, associate Professor, Institution of Science A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia, mindubaev@iopc.ru

E.V. Babynin, candidate of Sciences, associate Professor, Kazan (Volga region) federal university, Kazan, Russia, edward.b67@mail.ru

A.D. Voloshina, candidate of Sciences, Institution of Science A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia, microbi@iopc.ru

K.R. Khayarov, Kazan (Volga region) federal university, Kazan, Russia, ybadeev.61@mail.ru

E.K. Badeeva, candidate of Sciences, Institution of Science A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia, khayarov.kh@gmail.com

S.T. Minzanova, candidate of Sciences, associate Professor, Institution of Science A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, minzanova.salima@yandex.ru

L.G. Mironova, Institution of Science A.E. Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of Russian Academy of Sciences, Kazan, Russia, mironoval1963@gmail.com

Issue:  Volume 42, № 3

Rubric:  Biological sciences

Annotation:  The calculation showed that the transition metal salts concentration in the modified Pridhem-Gottlieb medium is too small for abiotic disproportionation of white phosphorus introduced in it. P4 excess, depending on the concentration, comprises in terms of Cu2+ from 25 to 25000 times! Hence, there is reason to talk about biodegradation. Inoculation of A. niger AM1 in medium containing just two sources of phosphorus (phosphate and white phosphorus) demonstrated that P4 does not exhibit toxic properties in relation to this microorganism. In the presence of white phosphorus it grows at the same rate as in the absence thereof. This is the only example of the lack of white phosphorus toxicity to a living organism. Our previous studies have demonstrated the absence of white phosphorus toxicity for Aspergillus niger AM1. However, the toxic properties of the substances are of different nature. It is of great interest to study the genotoxicity – a possible source of mutations. In the present work SOS-lux test has demonstrated genotoxicity of white phosphorus. This result is obtained for the first time – all the available literature sources reported no genotoxic properties of white phosphorus. Allium test showed the mitotoxic effect of white phosphorus on eukaryotic cells

Keywords:  detoxication, white phosphorus, culture medium, Aspergillus niger АМ1, sterilization, genotoxicity, Ames test, SOS-lux test

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