STUDY OF SOME TECHNOLOGICAL AND PHARMACOGNOSTIC PARAMETERS OF CALENDULAE FLORES

Author(s):  N.N. Boyko, candidate of Sciences, associate Professor, Belgorod National Research University, Belgorod, Russia, boykoniknik@gmail.com

E.T. Zhilyakova, Dr., Prof., Belgorod National Research University, Belgorod, Russia

Issue:  Volume 41, №1

Rubric:  Pharmaceutical Sciences

Annotation:  This article presents data about some pharmacognostic and technological parameters of Calendulae flores from eight manufacturers of Ukraine and the Russian Federation. Numerical values of “Loss on drying” 7.3±0.6 % wt., “Total ash” 11.2±0.5 % wt., “Extractive substances” 37.0±1.5 % wt., “Soluble ash” 5.2±0.4 % wt., “Potassium ion” 3.6±0.2 % wt., “Hydroxycinnamic acids” 2.1±0.1 % wt., and “Bulk den-sity” 0.32±0.02 g/cm³ for 0.1-0.5 mm fraction of grinded raw material, have been determined with gra-vimetry, ionometry, spectrophotometry methods. We have determined the range of the following parame-ters for Calendulae flores with the methods of mathematical statistics: “Loss on drying” may be in the range of 5.6-9.0 % wt., “Total ash” may be in the range of 9.9-12.5 % wt. However, samples of raw mate-rial with a smaller or larger value of this range may be found. “Extractive substances” may be in the range of 32.8-41.2 % wt. However, samples of raw material with a smaller or larger value of this range may be found. “Soluble ash” may be in the range of 4.1-6.3 % wt. “Potassium ion” may be in the range of 3.1-4.1 % wt. “Hydroxycinnamic acids” may be in the range of 1.8-2.5 % wt. “Bulk density” may be in the range of 0.26-0.38 g/cm³ for 0.1-0.5 mm fraction of grinded raw material. We have determined dependences between the content of extractive substances, soluble ash, potassium ion, hydroxycinnamic acids in raw materials and water content in the extractant, which are well described by logarithmic function.

Keywords:  Calendulae flores, technological and pharmacognostic parameters.

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