Steroid connections of the phytogenesis: phytoecdysones (phytoecdysteroids). Scientometric research of data of scientific and practical literature

Author(s):  A.E. Sukhanov, Northern State Medical University, Arkhangelsk, Russia

O.V. Buyuklinskaya, Northern State Medical University, Arkhangelsk, Russia

R.G. Koptyaeva, Northern State Medical University, Arkhangelsk, Russia

Issue:  Volume 40, №26

Rubric:  Pharmaceutical Sciences

Annotation:  Steroid compounds of plant origin (phytoecdysones or phytoecdysteroids) have been important in clinical medicine, have antifungal, antitumor activity, insecticidal and calling moult biological effects. However, the steroidal compound of plant origin, in particular, phytoecdysones (phytoecdysteroids), poorly studied with position identification in the tissues of plant organisms and methods physico-chemical analysis. The article provides a scientometric analysis of research information (reference documents) that contains the analytical array of scientific publications regarding the isolation, separation, purification, identification and quantification phytoecdysones (phytoecdysteroids) in the tissues of vascular plants in the patent bibliographic database "SciVerse Scopus" (publishing house "Elsevier"), using the criteria "keyword" and "keyword phrase". The most popular methods of analysis of the structure phytoecdysones (phytoecdysteroids) are high performance liquid chromatography with using of state standard samples of substances. The contribution of these methods in the chemical analysis of this class of compounds is 42.88% of all published methods of analysis for the class of compounds according to the "SciVerse Scopus". Other physico-chemical methods of research represented in the abstract bibliographic database in the same ratio: high performance liquid chromatography in tandem with mass spectrometry detection; the type of ionization of the investigated molecules – diode-array detection, electrospray, termolabilnye; magnetic resonance spectroscopy of the isotope carbon13, thin-layer chromatography at the stage of screening of choice for analysis of plant organisms. When analyzing the entire array of refereed papers abstracts bibliographic database "SciVerse Scopus" on the subject of use of modern physic-chemical methods of analysis of plant organisms on phytoecdysones (phytoecdysteroids) no mention of the following methods of analysis: high performance thin layer chromatography with densitometric quantification, radioimmunoassay analysis, turbulent chromatography with high performance liquid chromatography and mass spectrometry, mass spectrometry of different types of analyzers: quadrupole, time-of-flight; high-performance countercurrent chromatography, infrared spectroscopy Fourier, gel chromatography, spectrophotometry, supercritical fluid chromatography, high performance liquid chromatography in combination with mass spectrometry according to the type of orbital ion trap chemical ionization, atmospheric pressure photoionization at atmospheric pressure, the bombardment of fast atoms, which can be used in the methods of analytical and preparative chromatography

Keywords:  scientometric analysis, phytoecdysones (phytoecdysteroids)

Full text (PDF):  Download

Downloads count:  324