Clinical current and outcomes of the acute coronary syndrome

Author(s):  M.M. Kiselevich, candidate of Sciences, associate Professor, Belgorod National Research University, Belgorod, Russia, marianna1970@live.ru

О.А. Efremova, Dr., Prof., Belgorod National Research University, Belgorod, Russia

G.D. Petrova, candidate of Sciences, associate Professor, Belgorod National Research University, Belgorod, Russia

Issue:  Volume 41, № 4

Rubric:  Clinical Medicine

Annotation:  The article is devoted to the study of acute coronary syndrome. The analysis was conducted 1206 of case histories from middle-aged, elderly and senile patients with acute coronary syndrome. Evaluated by clinical symptoms and risk factors of acute coronary syndrome, laboratory tests, electrocardiography (ECG) in 12 leads and echocardiography. That was dominated by men (61.8 %), middle and old age (35.8 % and 39.0 % respectively). On the outcome of the disease number of discharged alive amounted to 92.0 % of people, but dead-8.0 %. The Group issued live acute coronary syndrome with ST segment elevation myocardial infarction (STEMI) was established for admission to 20.6 % of cases, and non-ST segment elevation myocardial infarction (NSTEMI) -79.4 %. In the dead with STEMI and NSTEMI were 47.4 % and 52.6 % respectively. In the clinical picture in the Group issued alive, a typical anginosus pain was observed at 19.7 % of patients, atypical clinical picture-34.2 %, in the dead of a typical anginosus pain-26.0 % of patients have atypical clinical picture-39.6 %. In some cases, the disease was as progressive angina (live-46.2 % of patients and in the dead-34.4 % of patients). Analysis of laboratory and instrumental data confirmed the diagnosis of unstable angina or heart attack the myocardium. The effectiveness of the treatment amounted to 92.0 %.Tthe results showed that patients with non-ST segment elevations (NSTEMI), which were later discharged from hospital; it was 4 times more than with ST segment elevation (STEMI). Deceased patients group STEMI and NSTEMI nobody. However, it was noted that most of the dead with NSTEMI accounted for patients with unstable angina. However, it was noted that most of the dead comprised patients with unstable angina. They all had a high degree of risk (male sex, advanced age, background and comorbidic diseases), the outcome also influenced the time from the beginning of symptoms before entering hospital and treatment tactics

Keywords:  acute coronary syndrome, coronary heart disease, myocardial infarction, clinical picture, diagnosis, disease outcomes

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