ELEMENTAL AND FATTY ACID COMPOSITION OF CAMPANULA ROTUNDIFOLIA L.

Author(s):  V.N. Bubenchikova, Dr., Prof., Kursk State Medical University, Kursk, Russia

E.A. Nikitin, Kursk State Medical University, Kursk, Russia, Evgeniy_nikitin_92@mail.ru

Issue:  Volume 41, №1

Rubric:  Pharmaceutical Sciences

Annotation:  Resume. This article presents the results of the study of the qualitative and quantitative composition min-eral elements and fatty acids of the herb of bell (Campanula rotundifolia L.). A reliable method of analy-sis of spectral emission, using the DFS-8-1 spectrography could make it possible to establish 28 minerals elements. Among them 10 essential elements and 5 probably necessary (conditionally essential), belongs to the vital (essential) elements). The mineral composition of the herb is composed by: Cu, Zn, Pb, Ag, Sn, Mo, Ga, Ba, Sr, P, Mn, Co, Ni, Ti, V, Cr, Be, Zr, Sc, Fe, K, Na , Ca, Mg, Al, Si, Li, B). In significant quantities were found potassium, magnesium, phosphorus and silicone that are related to condition-al important elements that accumulate in the herb. In the study of the qualitative and quantitative fatty acid composition in the herb, the method of Gas-liquid chromatography-mass spectrometry was used. Where were identified 17 compounds which were assigned to this class of compounds (Fatty Acids). Among them, the acids are predominant linoleic (1297.54 mg/kg), linolenic (1199.14 mg/kg) and palmitic (1186.10 mg/kg). In saturated fatty acids were found 11 compounds, they are 42.21% of the total amount of fatty acids. The unsaturated fatty acids which have pharmacological importance were identified 6 compounds, these compounds are predominant and their content is equivalent to 58.79% of the total amount of fatty acids. The scientific interest is represented by linoleic acid and linolenic acid that belong to the group of omega-3 fatty acids, which are essential unsaturated fatty acids.

Keywords:  mineral composition, fatty acid composition, Campanula rotundifolia L., gas-liquid chroma-tography, emission spectral analysis.

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